New Study Shows Cellular Manipulation Can Slow Down The Aging Process

Aging is part of the human experience. But not everyone ages the same way. The aging process is part of the genetic code in all humans. People have different genetic codes. That means cellular heath may not mean the same thing to people who don’t understand the importance of keeping their cells healthy as they grow older.

Understanding how cells stay healthy is a monumental task. There is a plethora of information about cellular health, and the proteins that keep cells functioning the way they should function. But most of that information doesn’t explain how to heal damaged cells or to replace those cells with new ones that make life more bearable as people hit their 70s and 80s.

Scientists now know biological aging or senescence is controllable. During senescence, body and brain cells stop dividing. One of the major issues that cause a condition known as the senescence-associated secretory phenotype or SASP is inflammation, according to the University of Edinburgh’s Medical Research Council’s Human Genetics Unit. The UK Edinburgh Centre scientists study the aging process that senescence triggers. Those scientists discovered manipulating the nuclear pores-gateways in cells where molecules enter the heart of the cell can prevent senescence-associated secretory phenotype. Scientists found the reorganization of DNA in the nucleus of cells triggers SASP.

According to the director of the Human Genetics Unit, Professor Wendy Bickmore, senescence isn’t as mysterious as it was a few years ago. Bickmore believes her findings give the scientific community a better understanding of biological aging and what actually causes cell damage. Her work and the work of her colleagues prove senescence can be a self-defense mechanism, but it also creates cellular malfunctions.

Slowing down the biological aging process and controlling the diseases that develop as the body ages are not out of reach, according to Professor Bickmore. Understanding how cells react to stress and damage will create new treatment medical methods that may cure serious aging issues.